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KMID : 0378019860290060112
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New Medical Journal
1986 Volume.29 No. 6 p.112 ~ p.116
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Clinical study for the Effectiveness of Cefmetazon in the Pediatric Field
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박병욱/Park, Byung Uk
황규태/정우영/오무영/김철호/이순용/Hwang, Kui Tae/Chung, Woo Yeong/Oh, Moo Young/Kim, Chul Ho/Lee, Soon Yong
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Abstract
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A clinical trial for the effectiveness of Cefmetazon, a new eephamycin analogue, was carried out and following results were obtained.
The daily dosage was 100mg/kg and given intravenously in 4 divided doses. During this period cefmetazone was administered alone.
The results were excellent in 5 cases, good in 10 cases and, ineffective in 5 cases on respiratory tract infections. Thus the rate of response was 75%.
In 13 cases of pneumonia, the results were excellent in 2 cases, good in 9 cases and ineffective in 2 cases, so the efficacy rate was 84.6%.
For the cases of soft tissue infections, the results were excellent in all 3 cases.
In the cases that staphylococcus aureus was isolated, the results were all effective.
All cases showed negative result in the skin test for hypersensitivity, but adverse effects
were observed in 3 cases including mild elevation of SGPT & SGOT in 2 cases and skin
rashes with urticaria in 1 case.
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KEYWORD
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